The LIT Therapy or Lymphocyte Immunisation Therapy is a procedure that is used to hep treat recurrent pregnancy losses. Recurrent pregnancy loss (RPL) is a condition which defines two or more failed pregnancies. The procedure involves the transfer of white blood cells from the father into the skin of the prospective mother. This is done to introduce the immune system of the husband so as to prepare the immune system of the woman for pregnancy and overcome possible immunologic causes of poor implantation.
When immunological causes for unsuccessful embryo implantations are suspected, LIT Therapy may be carried out. It is thought that because the developing embryo and foetal tissues are produced from both the mother and father’s DNA, the mother’s immune system mistakenly views proteins formed from the husband’s share of the genome as foreign and attacks the developing baby. Lymphocyte Immunization was created to make the mother’s immune system ready for pregnancy so that it can help acclimatize the potential mother’s body to foreign cells rather than fighting and destroying the embryo or foetus.
By introducing paternal proteins, antigens, and cellular structures to the developing embryo or foetus in a “friendly” manner before they may be deemed toxic and lead to the termination of early pregnancy, LIT is expected to alleviate this detrimental reaction.